Astros vs. Athletics Predictions & Picks: Odds, Moneyline, Spread - May 21

Sunday's game at Minute Maid Park has the Houston Astros (26-19) going head to head against the Oakland Athletics (10-37) at 2:10 PM ET on May 21. Our computer prediction projects a 6-3 victory for the Astros, who are favored by our model.

This contest's pitching matchup is set, as the Astros will send Framber Valdez (3-4) to the mound, while James Kaprielian (0-3) will take the ball for the Athletics.

Astros vs. Athletics Game Info & Odds

• When: Sunday, May 21, 2023 at 2:10 PM ET
• Where: Minute Maid Park in Houston, Texas
• How to Watch on TV: SportsNet SW
• Live Stream: Watch this game on Fubo!

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Astros vs. Athletics Score Prediction

Our pick for this matchup is Astros 6, Athletics 3.

Total Prediction for Astros vs. Athletics

• Total Prediction: Over 8.5 runs

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Read More About This Game

Astros Performance Insights

• In eight games as the favorite over the last 10 matchups, the Astros have a perfect record of 8-0.
• In its last 10 games with a total, Houston and its opponents are 3-7-0 when it comes to hitting the over.
• In their last game with a spread, the Astros failed to cover.
• The Astros have been favorites in 31 games this season and won 17 (54.8%) of those contests.
• Houston has not entered a game this season as bigger favorites on the moneyline than the -350 odds on them winning this game.
• The moneyline for this contest implies a 77.8% chance of a victory for the Astros.
• Houston has scored the 18th-most runs in the majors this season with 199 (4.4 per game).
• The Astros' 3.28 team ERA leads all league pitching staffs.

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