ULM professor awarded major grant for research - KNOE 8 News; KNOE-TV; KNOE.com |

ULM professor awarded major grant for research

Posted: Updated:

MONROE, La., (KNOE 8 News) - The National Institutes of Health awarded Dr. Khalid El Sayed, associate professor of pharmacy at the University of Louisiana at Monroe, $420,520 for his research project, "Design of novel c-Met inhibitors inspired by olive phenolics."

ULM President Dr. Nick J. Bruno said, "I am very proud of Dr. El Sayed and what he has accomplished thus far. The continuation of these kinds of grants will further build his reputation as a researcher. This also signifies the importance of our College of Pharmacy and its relevance to the state, the region, and the university as a whole."

The research project will use a natural compound found in extra virgin olive oil and other related natural compounds as possible dietary supplements to control breast cancer and to enhance the therapeutic effects of current anticancer drugs.

"Dr. El Sayed continues to have success in the area of cancer therapeutics discovery and development from natural products," said Dr. Benny Blaylock, Dean of the College of Pharmacy. "The information from this research will add important information for use in both treatment and prevention of breast and prostate cancer. The College of Pharmacy is very proud of the research being done by Dr. El Sayed and other members of the Department of Basic Pharmaceutical Sciences."

The research is derived from studies focused on the eating habits and disease occurrence of those living in the Mediterranean, El Sayed said.

"Nature is still the single most important drug source," said El Sayed. "About 75 percent of today's anticancer drugs are natural products or based on natural origin. The Mediterranean diet includes extensive use of olive oil in its ingredients, which correlates to lower incidences of cardiovascular disease, age-related cognitive disease and cancer."

The project also includes the use of computer software to make new synthetic compounds similar to the olive-derived compounds. The synthetic compounds will have significant improvement in anticancer activity, El Sayed said.

"These compounds showed activity against several metastatic prostate and breast cancers," said El Sayed. "The proposed research will develop novel c-Met—an important enzyme for several metastatic tumor types—and cancer inhibitors for future pre-clinical and clinical studies."

El Sayed explained his expectations for the project. "Our long-term goal is to utilize the ability of olive oil to inhibit the activation of the c-Met enzyme and use it as a dietary supplement to synergize the effects of chemotherapeutics."

El Sayed continued, "This project would not have been successful without the thoughtful contribution, support, and hard work of collaborators and graduate students from the ULM College of Pharmacy. Faculty members of the ULM College of Pharmacy believe they have the talent, persistence, skills, experience, and knowledge to achieve the establishment of a 'Louisiana Drug Discovery Center' in collaboration with other Louisiana institutions. This success is a step forward towards this direction."

While at ULM, El Sayed has received $1,180,000 in research support from Louisiana Biomedical Research Network, Philip Morris, the American Society of Pharmacognosy, the American Foundation for Pharmaceutical Education, and several small companies. He has also received $278,000 from the Louisiana Board of Regents for equipment funding. In collaboration with his pharmacy colleagues, El Sayed has been awarded three U.S. patents for cancer research. He has taught at ULM since 2001.

  • Most Popular StoriesMost Popular StoriesMore>>

  • Security officer recognized for helping catch felon

    Security officer recognized for helping catch felon

    Thursday, April 24 2014 12:15 AM EDT2014-04-24 04:15:48 GMT
    MONROE, La. (KNOE 8 News)- A Pecanland Mall security guard was appreciated for her bravery and tactical skills on apprehending a criminal.Angel Cook was recognized as the south central region security officer of the year.On January 30. Cook helped police find convicted felon Terresz Robinson.Cook noticed Robinson in the mall and immediately started to keep a close eye on him while alerting police.She credits her colleagues for helping in the arrest.Terresz Robinson was found guilty of second ...
    MONROE, La. (KNOE 8 News)- A Pecanland Mall security guard was appreciated for her bravery and tactical skills on apprehending a criminal.Angel Cook was recognized as the south central region security officer of the year.On January 30. Cook helped police find convicted felon Terresz Robinson.Cook noticed Robinson in the mall and immediately started to keep a close eye on him while alerting police.She credits her colleagues for helping in the arrest.Terresz Robinson was found guilty of second ...
  • Head-on crash kills Rayville man

    Head-on crash kills Rayville man

    Wednesday, April 23 2014 11:41 AM EDT2014-04-23 15:41:23 GMT
    RAYVILLE, La. (KNOE 8 News) -On April 22, 2014, at 8:00 p.m., Troopers assigned to Louisiana State Police Troop F responded to a two vehicle fatal crash on Whitehall Road south of Louisiana Highway 15.
    RAYVILLE, La. (KNOE 8 News) -On April 22, 2014, at 8:00 p.m., Troopers assigned to Louisiana State Police Troop F responded to a two vehicle fatal crash on Whitehall Road south of Louisiana Highway 15.
  • Corrections officer arrested for sexual misconduct with inmate

    Corrections officer arrested for sexual misconduct with inmate

    Wednesday, April 23 2014 3:00 PM EDT2014-04-23 19:00:59 GMT
    DELHI, La. (KNOE 8 News) - Tuesday, April 22, 2014 at approximately PM, Richland Parish Sheriff’s personnel received a complaint of sexual misconduct from an offender incarcerated at Richland Parish Detention Center.
    DELHI, La. (KNOE 8 News) - Tuesday, April 22, 2014 at approximately PM, Richland Parish Sheriff’s personnel received a complaint of sexual misconduct from an offender incarcerated at Richland Parish Detention Center.
  • Dean Hart, Jr. given bail

    Dean Hart, Jr. given bail

    Wednesday, April 23 2014 5:02 PM EDT2014-04-23 21:02:22 GMT
    MONROE, La. (KNOE 8 News) - A judge has given Dean Hart, Jr. the opportunity to post bail with conditions.Our reporter is in the courtroom, and we will update this story as it comes available.
    MONROE, La. (KNOE 8 News) - A judge has given Dean Hart, Jr. the opportunity to post bail with conditions.Our reporter is in the courtroom, and we will update this story as it comes available.
  • Vieux Carre put up for auction

    Vieux Carre put up for auction

    Wednesday, April 23 2014 12:15 PM EDT2014-04-23 16:15:30 GMT
    MONROE, La. (KNOE 8 News) - The Vieux Carre store and restaurant on North 18th street is closed down, and the entire moveable contents are up for auction.
    MONROE, La. (KNOE 8 News) - The Vieux Carre store and restaurant on North 18th street is closed down, and the entire moveable contents are up for auction.
  • Legislature discuss payday loans

    Legislature discuss payday loans

    Wednesday, April 23 2014 11:43 PM EDT2014-04-24 03:43:02 GMT
    MONROE, La. (KNOE 8 News)- Legislators discussed a bill that would limit the amount of times an individual can take out loans from a payday lender within a years period.This after a bill that suggested interest rates be capped at 36% was shot down. Senator Ben Nevers of Bogalusa is the author of both bills.ULM economist Robert Eisenstadt says limiting the amount of loans taken out won't solve the problem of payday lending.Representative Erich Ponti of Baton Rouge opposes a bill that will limi...
    MONROE, La. (KNOE 8 News)- Legislators discussed a bill that would limit the amount of times an individual can take out loans from a payday lender within a years period.This after a bill that suggested interest rates be capped at 36% was shot down. Senator Ben Nevers of Bogalusa is the author of both bills.ULM economist Robert Eisenstadt says limiting the amount of loans taken out won't solve the problem of payday lending.Representative Erich Ponti of Baton Rouge opposes a bill that will limi...
  • Hamburg man shoots and kills neighbor

    Hamburg man shoots and kills neighbor

    Monday, April 21 2014 2:41 PM EDT2014-04-21 18:41:41 GMT
    HAMBURG, Ar. (KNOE 8 News) - Ashley County authorities have arrested a Hamburg man after he shot and killed his neighbor on Easter Sunday.
    HAMBURG, Ar. (KNOE 8 News) - Ashley County authorities have arrested a Hamburg man after he shot and killed his neighbor on Easter Sunday.
  • New facility bringing almost 700 jobs to Shreveport

    New facility bringing almost 700 jobs to Shreveport

    Friday, October 26 2012 5:57 PM EDT2012-10-26 21:57:40 GMT
    SHREVEPORT, La., (KNOE 8 News) - Project could possibly create another 2000+ jobs as well in time.
    SHREVEPORT, La., (KNOE 8 News) - Project could possibly create another 1500+ indirect jobs as well in time.
Powered by WorldNow
All content © Copyright 2000 - 2014 WorldNow and KNOE. All Rights Reserved.
For more information on this site, please read our Privacy Policy and Terms of Service.